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Multiple pathogen structure

Usage

multiple(data, case_timeseries, component_pathogen_timeseries, time = NULL)

Arguments

data

dataframe containing columns with all relevant data, or a time series object (ts, xts, zoo, tsibble, etc.)

case_timeseries

Column name containing case counts. Must be numeric or a units object from the units package.

component_pathogen_timeseries

vector of column names with additional pathogen case count timeseries to model. Must be numeric or a units object from the units package.

time

Column name with time data. Required for non-time-series input data. Flexible format - can be date, index, or others, accepted as index identifiers in the tsibble time format. Optional when data is a time series class object (ts, mts, xts, zoo, zooreg, tsibble) as the time index will be automatically detected.

Value

named list including pathogen_structure, pathogen_names, and data of class EpiStrainDynamics.pathogen_structure

See also

Other pathogen_structure: single(), subtyped()

Examples

# Using a data frame
multiple(
  data = sarscov2,
  case_timeseries = "cases",
  component_pathogen_timeseries = c("alpha", "delta", "omicron", "other"),
  time = "date"
)
#> $pathogen_structure
#> [1] "multiple"
#> 
#> $pathogen_names
#> [1] "alpha"   "delta"   "omicron" "other"  
#> 
#> $validated_tsbl
#> # A tsibble: 830 x 6 [1D]
#>    date       case_timeseries alpha delta omicron other
#>    <date>               <dbl> <int> <int>   <int> <int>
#>  1 2020-09-23            7096     0     0       0    10
#>  2 2020-09-24            7682     0     0       0     7
#>  3 2020-09-25            7318     0     0       0     9
#>  4 2020-09-26            6810     0     0       0    15
#>  5 2020-09-27            7023     0     0       0     5
#>  6 2020-09-28            9983     0     0       0     6
#>  7 2020-09-29           10366     0     0       0    23
#>  8 2020-09-30           12717     0     0       0    54
#>  9 2020-10-01           13357     0     0       0    32
#> 10 2020-10-02           13854     0     0       0    15
#> # ℹ 820 more rows
#> 
#> $data
#> $data$case_timeseries
#>   [1]   7096   7682   7318   6810   7023   9983  10366  12717  13357  13854
#>  [11]  11667  11953  16753  17250  18573  18425  15893  12648  12202  19671
#>  [21]  19116  19920  18606  17915  14882  14311  25872  25613  25714  23475
#>  [31]  21694  16434  15895  26807  24351  23901  23614  22890  16673  15970
#>  [41]  31925  25943  24027  24063  23659  18766  20244  31510  27789  27757
#>  [51]  24826  24388  18223  16233  26952  23488  21076  18041  17100  12533
#>  [61]  11895  19024  16679  16814  14761  14554  11086  10852  18198  16684
#>  [71]  16676  15860  15834  12893  13731  21584  21065  21909  22916  24390
#>  [81]  19588  22266  35197  34378  35427  34437  36419  25589  33066  48192
#>  [91]  46475  42936  32392  14419  41110  48520  46408  83090  72161  53947
#> [101]  32482  61654  56335  77972  66638  58784  53187  48105  40035  37174
#> [111]  58592  50647  46509  43472  41452  31250  29592  45957  40525  35986
#> [121]  32502  30330  22344  17554  30737  27730  26303  24773  22434  17167
#> [131]  15783  22972  20265  19914  18493  16307  12320  11664  16194  14225
#> [141]  13899  13139  12573   9035   8995  14735  12939  11942  11793  10728
#> [151]   8313   8098  11657   9763   8847   8024   6782   4949   4873   7192
#> [161]   6918   6172   5937   5467   4628   4410   6890   6488   6250   5933
#> [171]   5717   4381   4425   6703   5863   5978   5632   5180   4247   5390
#> [181]   6459   5484   6224   5616   4567   3731   5030   4196   3779   3966
#> [191]   3674   2747   2508   2412   2744   3313   3253   3147   2953   2380
#> [201]   2376   2881   2495   2512   2345   2347   1722   2584   2738   2541
#> [211]   2708   2409   2020   1564   2119   2626   2178   2499   2230   1825
#> [221]   1433   1521   2084   2553   2569   2326   1982   1609   2307   2809
#> [231]   2329   2335   2182   1938   1628   1923   2858   2812   2813   2517
#> [241]   2367   2000   2326   3369   3427   3922   3747   3589   3000   3164
#> [251]   3897   5431   6168   6258   5861   4731   5534   7946   7896   8210
#> [261]   8043   7619   6284   7135  10362  10800  11052  11106  10320   8447
#> [271]  10087  16308  17402  18351  18714  18169  16301  18502  28418  28199
#> [281]  28923  28794  26339  24010  25170  34919  36060  38597  34020  32804
#> [291]  28379  30503  44511  47707  54910  62000  55264  38476  36182  47924
#> [301]  39876  35548  31278  27817  22852  22187  29981  29582  30237  28432
#> [311]  24749  20570  20985  29840  30473  32338  31660  28035  22540  22887
#> [321]  32162  31518  33350  31726  28974  25057  25327  36907  37920  38739
#> [331]  36501  32231  28536  28743  39715  37682  38777  37613  33745  27601
#> [341]  26136  34774  45212  43532  42328  38633  31810  31803  44929  38619
#> [351]  35849  33974  29187  23533  24060  34658  31435  30414  29710  29479
#> [361]  26645  31084  40768  38848  36756  35851  32108  28567  32083  41589
#> [371]  36548  34837  32604  29058  26316  32059  43733  39279  39264  38465
#> [381]  35612  32306  36418  50304  48321  47775  46419  43560  37878  43752
#> [391]  57743  52529  51661  45194  40664  35103  35764  47466  42124  43045
#> [401]  41391  40251  33569  34814  45109  38019  35986  33662  30318  27436
#> [411]  30586  44126  42246  42942  40999  37763  32885  35532  50948  46430
#> [421]  45895  44062  39606  35335  37250  50733  48197  46772  43425  39330
#> [431]  33303  39706  56289  55695  54820  50319  45667  38784  41051  59694
#> [441]  56258  58827  56995  52492  48594  53158  87169 102788 112703 106055
#> [451]  95897  88883  89133 133966 150293 161560 160633 137268  70363 116287
#> [461] 195011 212469 272798 236576 188567 118275 181068 229901 275647 222174
#> [471] 172980 120287  93615  95790 132959 115245 103219  96412  86325  77950
#> [481]  98097 131514 118857 111760 100324  91730  81733 102365 127364 113202
#> [491] 108668  96201  84026  73512  87702 105051  93949  88418  76644  63264
#> [501]  52305  60552  76483  69661  64339  52293  44559  37529  41755  54745
#> [511]  52502  51572  44716  33241  34647  37720  45132  39188  36477  30631
#> [521]  27837  25089  31360  44649  44795  46179  43761  41408  38759  49026
#> [531]  68520  70112  73531  70510  67030  62078  75739  99834  93708  91751
#> [541]  82853  75285  67417  81054 109286  99095  94185  82905  72430  61456
#> [551]  68336  92857  80126  73643  54791  47462  37592  42179  53727  49101
#> [561]  44750  38709  32988  27885  30952  37371  33771  31685  26639  21617
#> [571]  19925  20144  25223  25772  21457  18464  15703  13210  14714  17109
#> [581]  14560  13055  11608  10012   8354   9034  11907  13318  11672  10221
#> [591]   8954   7517   9062  10702   9748   8725   7642   6942   6120   7973
#> [601]   9417   8286   7638   6820   5821   5019   5997   7313   6679   6293
#> [611]   5753   5409   4988   5680   7115   7093   7011   6209   6635   7492
#> [621]   9815  11747  11411  11784  11319  10784  10077  12693  15272  15141
#> [631]  14837  14225  13919  13623  16997  19942  20896  20873  19590  18350
#> [641]  16800  20778  25104  25041  24601  24240  23650  21961  27780  33704
#> [651]  31415  29698  26454  24611  21246  25096  29826  26946  23856  21100
#> [661]  18359  15017  17236  18718  16670  16169  14158  12378   9934  11275
#> [671]  13299  11725  10544   9329   8508   7325   8426   9835   9170   8353
#> [681]   7296   6548   5420   6547   8068   7309   6748   6193   5339   4495
#> [691]   5363   6424   5559   5032   4564   4012   3502   4085   5224   4778
#> [701]   4554   3796   3451   3112   3439   4662   5226   4616   4350   3808
#> [711]   3417   4288   5125   4578   4235   3747   3553   3268   4347   5308
#> [721]   5148   4973   4634   4134   3521   4339   6166   7828   7553   6815
#> [731]   6485   5719   7240   8618   8255   8414   7895   7615   7065   9204
#> [741]  11692  10965  10231   9389   8950   7053   8558  10497   9461   8769
#> [751]   8134   7970   6442   7780  10005   8235   7598   6576   6297   4968
#> [761]   5523   6807   5665   5449   4855   4401   3583   4271   5129   4549
#> [771]   4014   3678   3107   2665   3267   4321   3829   3576   3205   2893
#> [781]   2433   2912   3923   3534   3260   3037   2773   2431   2890   3938
#> [791]   3805   3616   3329   2902   2551   3448   4639   4386   3980   3505
#> [801]   3596   2748   3786   5325   5241   5195   4537   4216   3570   4631
#> [811]   6986   7111   6533   6094   6084   4743   5772   9073   8631   7802
#> [821]   6877   5741   4132   3694   4950   6605   8419   7718   6126   4287
#> 
#> $data$component_pathogens
#>         [,1] [,2] [,3] [,4] [,5] [,6] [,7] [,8] [,9] [,10] [,11] [,12] [,13]
#> alpha      0    0    0    0    0    0    0    0    0     0     0     0     0
#> delta      0    0    0    0    0    0    0    0    0     0     0     0     0
#> omicron    0    0    0    0    0    0    0    0    0     0     0     0     0
#> other     10    7    9   15    5    6   23   54   32    15    23     8    35
#>         [,14] [,15] [,16] [,17] [,18] [,19] [,20] [,21] [,22] [,23] [,24] [,25]
#> alpha       0     0     0     0     0     0     0     0     0     0     0     0
#> delta       0     0     0     0     0     0     0     0     0     0     0     0
#> omicron     0     0     0     0     0     0     0     0     0     0     0     0
#> other      39    45    25    18    12    25    47    34    18    11    23    24
#>         [,26] [,27] [,28] [,29] [,30] [,31] [,32] [,33] [,34] [,35] [,36] [,37]
#> alpha       0     0     0     0     0     0     0     0     0     0     0     0
#> delta       0     0     0     0     0     0     0     0     0     0     0     0
#> omicron     0     0     0     0     0     0     0     0     0     0     0     0
#> other      33    47    55    46    21     7     8     9    10     3     3     4
#>         [,38] [,39] [,40] [,41] [,42] [,43] [,44] [,45] [,46] [,47] [,48] [,49]
#> alpha       0     0     3     1     0     0     0     0     1     2     0     0
#> delta       0     0     0     0     0     0     0     0     0     0     0     0
#> omicron     0     0     0     0     0     0     0     0     0     0     0     0
#> other       1     3    22    25     7     6    14    32    14    10    21    25
#>         [,50] [,51] [,52] [,53] [,54] [,55] [,56] [,57] [,58] [,59] [,60] [,61]
#> alpha       1     0     0     0     2     4     1     1     3     3     3     2
#> delta       0     0     0     0     0     0     0     0     0     0     0     0
#> omicron     0     0     0     0     0     0     0     0     0     0     0     0
#> other      18    20    25    26    10    38    14     4    13    11     8    14
#>         [,62] [,63] [,64] [,65] [,66] [,67] [,68] [,69] [,70] [,71] [,72] [,73]
#> alpha       4     6    14     4     4     7     6     3     4     8     0     1
#> delta       0     0     0     0     0     0     0     0     0     0     0     0
#> omicron     0     0     0     0     0     0     0     0     0     0     0     0
#> other      14    14     7     6    10     6    15    11    14     4     1     0
#>         [,74] [,75] [,76] [,77] [,78] [,79] [,80] [,81] [,82] [,83] [,84] [,85]
#> alpha       0     0    18    16    12    12    14     7    10    27    63    57
#> delta       0     0     0     0     0     0     0     0     0     0     0     0
#> omicron     0     0     0     0     0     0     0     0     0     0     0     0
#> other       0     5     5    11    11     7     7     5     5    38    34    52
#>         [,86] [,87] [,88] [,89] [,90] [,91] [,92] [,93] [,94] [,95] [,96] [,97]
#> alpha      64    47    17    30    52    65    69     0     0     1    48    60
#> delta       0     0     0     0     0     0     0     0     0     0     0     0
#> omicron     0     0     0     0     0     0     0     0     0     0     0     0
#> other      46    34    21    16    29    32    29     0     0     0    27    21
#>         [,98] [,99] [,100] [,101] [,102] [,103] [,104] [,105] [,106] [,107]
#> alpha     111    68     15      0     35     50    125     93     67     50
#> delta       0     0      0      0      0      0      0      0      0      0
#> omicron     0     0      0      0      0      0      0      0      0      0
#> other      41    13     14      0     22     18     39     28     21      9
#>         [,108] [,109] [,110] [,111] [,112] [,113] [,114] [,115] [,116] [,117]
#> alpha       55     40     48     81     75     70     38     46     43     45
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other       15     11     17     10     18     18      4      2     12      4
#>         [,118] [,119] [,120] [,121] [,122] [,123] [,124] [,125] [,126] [,127]
#> alpha       67     54     53     39     34     29     17     19     51     53
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        7      4     17      2      6      5      4      6      1      4
#>         [,128] [,129] [,130] [,131] [,132] [,133] [,134] [,135] [,136] [,137]
#> alpha       44     39     22     47     36     26     24     31     18     29
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        4      5      3      5      4      0      1      1      0      1
#>         [,138] [,139] [,140] [,141] [,142] [,143] [,144] [,145] [,146] [,147]
#> alpha        2     33     25     29     23     20     10      8     22     26
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      1      2      1      1      0      2      1      0
#>         [,148] [,149] [,150] [,151] [,152] [,153] [,154] [,155] [,156] [,157]
#> alpha       17      6      5      6      8     13     16     13     11     10
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      1      0      1      0      0      1
#>         [,158] [,159] [,160] [,161] [,162] [,163] [,164] [,165] [,166] [,167]
#> alpha        7     11     10     14     15     11      4      9      6     13
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      1      2      0      3      0      0      1      0      0
#>         [,168] [,169] [,170] [,171] [,172] [,173] [,174] [,175] [,176] [,177]
#> alpha        6     11     10     15     12      8     20      6      6     12
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      1      0      0      0      0      0      2      0      0
#>         [,178] [,179] [,180] [,181] [,182] [,183] [,184] [,185] [,186] [,187]
#> alpha        4      7      8     11      8      8     13      4      8      8
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      1      0      0      0      0      0      0      1      0
#>         [,188] [,189] [,190] [,191] [,192] [,193] [,194] [,195] [,196] [,197]
#> alpha       10     11      9      8      5      3      0      5      7      8
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        1      0      0      0      0      0      0      0      0      0
#>         [,198] [,199] [,200] [,201] [,202] [,203] [,204] [,205] [,206] [,207]
#> alpha        2      5      6     10      8      4      5      6      3      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,208] [,209] [,210] [,211] [,212] [,213] [,214] [,215] [,216] [,217]
#> alpha        1      5      7      3      2      3      3      1      3      4
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      1      0      0      0      0      0      0
#>         [,218] [,219] [,220] [,221] [,222] [,223] [,224] [,225] [,226] [,227]
#> alpha        2      2      5      3      0      5      1      0      1      2
#> delta        1      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,228] [,229] [,230] [,231] [,232] [,233] [,234] [,235] [,236] [,237]
#> alpha        2      0      1      2      3      2      2      0      0      4
#> delta        1      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,238] [,239] [,240] [,241] [,242] [,243] [,244] [,245] [,246] [,247]
#> alpha        1      2      1      0      0      2      0      2      2      2
#> delta       10      0      0      4      2      1      4      3      3      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,248] [,249] [,250] [,251] [,252] [,253] [,254] [,255] [,256] [,257]
#> alpha        1      0      1      0      4      0      2      2      0      0
#> delta        1     10      2      3      7      6      2     10      6      3
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      1      0      0      0      0      0
#>         [,258] [,259] [,260] [,261] [,262] [,263] [,264] [,265] [,266] [,267]
#> alpha        0      0      1      2      1      1      0      2      1      1
#> delta        6     13      8      6      6     10      6     20      9      7
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,268] [,269] [,270] [,271] [,272] [,273] [,274] [,275] [,276] [,277]
#> alpha        0      1      0      0      0      2      0      2      0      0
#> delta        9     18     16      6     22     21     26     26     22     24
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      1      0      1      0      0      0
#>         [,278] [,279] [,280] [,281] [,282] [,283] [,284] [,285] [,286] [,287]
#> alpha        1      0      1      0      1      1      0      1      0      0
#> delta       24     37     29     40     30     39     21     23     55     61
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,288] [,289] [,290] [,291] [,292] [,293] [,294] [,295] [,296] [,297]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta       83     61     63     55     42     73     80     66     94     60
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,298] [,299] [,300] [,301] [,302] [,303] [,304] [,305] [,306] [,307]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta       58     79    111    106    111     94    106     70     55     42
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      1
#>         [,308] [,309] [,310] [,311] [,312] [,313] [,314] [,315] [,316] [,317]
#> alpha        0      0      0      0      0      0      0      0      1      0
#> delta       28     37     54     70     49     49     66     85     70     94
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,318] [,319] [,320] [,321] [,322] [,323] [,324] [,325] [,326] [,327]
#> alpha        0      0      0      0      0      1      0      0      0      0
#> delta       56     40     39     48     64     86     71     64     49     56
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,328] [,329] [,330] [,331] [,332] [,333] [,334] [,335] [,336] [,337]
#> alpha        0      1      0      0      0      0      1      0      0      0
#> delta       70     97     86     49     58     74     65     68     92     80
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,338] [,339] [,340] [,341] [,342] [,343] [,344] [,345] [,346] [,347]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta       73     66     58     53     48    106     82     83     72     73
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,348] [,349] [,350] [,351] [,352] [,353] [,354] [,355] [,356] [,357]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta       58     74     93    107    101     74     66     50     99     86
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,358] [,359] [,360] [,361] [,362] [,363] [,364] [,365] [,366] [,367]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta       75     78     69     70     77     76     88     98    103     96
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,368] [,369] [,370] [,371] [,372] [,373] [,374] [,375] [,376] [,377]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta      103     93    102    119    113    100    104    111    118    127
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,378] [,379] [,380] [,381] [,382] [,383] [,384] [,385] [,386] [,387]
#> alpha        0      0      0      0      0      0      0      0      0      1
#> delta      112    143    122    134    141     87    103    124    161    145
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,388] [,389] [,390] [,391] [,392] [,393] [,394] [,395] [,396] [,397]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta      151    178    156    188    155    179    159    126    141    173
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,398] [,399] [,400] [,401] [,402] [,403] [,404] [,405] [,406] [,407]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta      161    161    184    147    110     94    149    122    150    148
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,408] [,409] [,410] [,411] [,412] [,413] [,414] [,415] [,416] [,417]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta      148    116     94    119    113    124    126    110     95    105
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,418] [,419] [,420] [,421] [,422] [,423] [,424] [,425] [,426] [,427]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta       96    131    166    123     93    116    106    119    119    147
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,428] [,429] [,430] [,431] [,432] [,433] [,434] [,435] [,436] [,437]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta      150    128     93    111     97    122    146    125    136    117
#> omicron      0      0      0      0      0      2      0      0      0      1
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,438] [,439] [,440] [,441] [,442] [,443] [,444] [,445] [,446] [,447]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta      121    108     95    137    106    123     85     81     84     95
#> omicron      2      5      6     10     16      7     15     15     26     64
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,448] [,449] [,450] [,451] [,452] [,453] [,454] [,455] [,456] [,457]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta      117    133    111     94     72     70    122    112     87     55
#> omicron     88    124    111    138    150    164    256    331    283    220
#> other        2      0      0      0      0      0      0      1      0      0
#>         [,458] [,459] [,460] [,461] [,462] [,463] [,464] [,465] [,466] [,467]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0     38     37     28     29     15      0     12
#> omicron      0      0      4    335    510    525    520    322      2    410
#> other        0      0      0      1      0      0      0      0      0      0
#>         [,468] [,469] [,470] [,471] [,472] [,473] [,474] [,475] [,476] [,477]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta       15     22     13     10      6      5     13      7      7      5
#> omicron    573    594    579    570    495    410    421    436    500    469
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,478] [,479] [,480] [,481] [,482] [,483] [,484] [,485] [,486] [,487]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        2      3      7      3      4      3      2      1      2      1
#> omicron    334    337    348    341    411    452    329    258    321    327
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,488] [,489] [,490] [,491] [,492] [,493] [,494] [,495] [,496] [,497]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      1      2      0      0      2      0      2      1      0
#> omicron    295    408    450    425    352    303    356    388    475    517
#> other        0      0      0      0      0      0      0      0      1      0
#>         [,498] [,499] [,500] [,501] [,502] [,503] [,504] [,505] [,506] [,507]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        1      0      0      1      0      0      0      2      0      1
#> omicron    501    398    372    319    359    423    400    417    346    281
#> other        0      1      0      0      0      0      0      0      0      0
#>         [,508] [,509] [,510] [,511] [,512] [,513] [,514] [,515] [,516] [,517]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      1      0      0      0      0      0      0      0
#> omicron    316    255    282    329    308    275    201    226    269    265
#> other        0      0      0      2      0      0      0      0      0      0
#>         [,518] [,519] [,520] [,521] [,522] [,523] [,524] [,525] [,526] [,527]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        1      0      0      0      0      0      0      0      0      0
#> omicron    272    274    253    229    237    280    283    289    254    233
#> other        3      1      1      0      0      0      1      0      0      0
#>         [,528] [,529] [,530] [,531] [,532] [,533] [,534] [,535] [,536] [,537]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      2      0      0      0      0      0      0      0
#> omicron    262    300    282    380    385    430    451    435    420    522
#> other        0      0      0      1      0      3      2      2      1      5
#>         [,538] [,539] [,540] [,541] [,542] [,543] [,544] [,545] [,546] [,547]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      1
#> omicron    563    649    614    463    427    394    507    702    752    718
#> other        3      3      7      3      0      4      7      6      3      5
#>         [,548] [,549] [,550] [,551] [,552] [,553] [,554] [,555] [,556] [,557]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    725    590    662    560    831    860    811    673    489    474
#> other        2      5      9      6      9      6     11      3      4      3
#>         [,558] [,559] [,560] [,561] [,562] [,563] [,564] [,565] [,566] [,567]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    479    639    648    558    458    351    294    399    578    588
#> other        4      6      4      6      2      2      4      1      3      4
#>         [,568] [,569] [,570] [,571] [,572] [,573] [,574] [,575] [,576] [,577]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    585    480    367    239      3    355    413    432    370    314
#> other        3      4      0      1      0      4      6      4      1      9
#>         [,578] [,579] [,580] [,581] [,582] [,583] [,584] [,585] [,586] [,587]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    276    204    252    285    196    183    152    133    101    157
#> other        2      2      0      1      0      1      0      0      2      4
#>         [,588] [,589] [,590] [,591] [,592] [,593] [,594] [,595] [,596] [,597]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    166    173    176    109    109    108    145    158    167    127
#> other        1      0      0      2      2      3      1      4      0      0
#>         [,598] [,599] [,600] [,601] [,602] [,603] [,604] [,605] [,606] [,607]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     99    101     88    139    131    154    150    106     78     83
#> other        7      0      0      1      3      1      0      1      1      1
#>         [,608] [,609] [,610] [,611] [,612] [,613] [,614] [,615] [,616] [,617]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    110    118    113     99     85     81     69    115    123    111
#> other        0      0      0      1      0      1      1      0      0      3
#>         [,618] [,619] [,620] [,621] [,622] [,623] [,624] [,625] [,626] [,627]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     84      1    116    103    171    206    190    170    192    119
#> other        0      0      0      0      1      1      2      0      0      0
#>         [,628] [,629] [,630] [,631] [,632] [,633] [,634] [,635] [,636] [,637]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    121    225    187    229    162    156    156    162    253    284
#> other        0      0      2      0      0      0      1      0      1      1
#>         [,638] [,639] [,640] [,641] [,642] [,643] [,644] [,645] [,646] [,647]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    271    245    256    208    228    330    322    325    297    270
#> other        0      0      0      1      0      0      1      0      2      0
#>         [,648] [,649] [,650] [,651] [,652] [,653] [,654] [,655] [,656] [,657]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    229    230    283    299    321    297    241    173    155    291
#> other        0      0      0      0      0      0      1      1      0      0
#>         [,658] [,659] [,660] [,661] [,662] [,663] [,664] [,665] [,666] [,667]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    325    283    312    268    226    151    287    334    373    348
#> other        0      2      0      0      1      1      1      0      1      0
#>         [,668] [,669] [,670] [,671] [,672] [,673] [,674] [,675] [,676] [,677]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    336    180    167    427    340    311    262    181    113     92
#> other        0      0      0      4      1      0      0      2      0      0
#>         [,678] [,679] [,680] [,681] [,682] [,683] [,684] [,685] [,686] [,687]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    201    138    101    118     97     49     27    171    112     69
#> other        0      0      0      0      1      0      0      0      0      0
#>         [,688] [,689] [,690] [,691] [,692] [,693] [,694] [,695] [,696] [,697]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     95     94     58     43    180    103    105     88     92     63
#> other        0      0      0      0      0      0      0      0      0      2
#>         [,698] [,699] [,700] [,701] [,702] [,703] [,704] [,705] [,706] [,707]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     43    162    116    105     64     75     31     23     72    114
#> other        0      0      0      0      0      0      0      0      0      1
#>         [,708] [,709] [,710] [,711] [,712] [,713] [,714] [,715] [,716] [,717]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     42    179     95     59     50    187    125     55     30     38
#> other        1      0      0      0      0      0      0      0      0      0
#>         [,718] [,719] [,720] [,721] [,722] [,723] [,724] [,725] [,726] [,727]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     55     55    182     95    114    119    106     69     22     57
#> other        0      0      0      1      0      3      1      1      0      0
#>         [,728] [,729] [,730] [,731] [,732] [,733] [,734] [,735] [,736] [,737]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    228    179    179    138     83     92    227    167    180    175
#> other        0      0      0      0      1      1      4      2      0      0
#>         [,738] [,739] [,740] [,741] [,742] [,743] [,744] [,745] [,746] [,747]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    102     61     95    274    237    262    301    246    126     90
#> other        0      1      2      2      1      0      2      1      0      2
#>         [,748] [,749] [,750] [,751] [,752] [,753] [,754] [,755] [,756] [,757]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    369    257    188    118    259    102    101    398    242    162
#> other        2      1      1      2      3      1      4     12      9      7
#>         [,758] [,759] [,760] [,761] [,762] [,763] [,764] [,765] [,766] [,767]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     65    247    105     56    207     78    254    170    177     70
#> other        2      8      2      0      2      1      5      2      5      2
#>         [,768] [,769] [,770] [,771] [,772] [,773] [,774] [,775] [,776] [,777]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     68    177    124    121    119    126     51     65    135    110
#> other        1      6      5      4      5      2      2      2      6      2
#>         [,778] [,779] [,780] [,781] [,782] [,783] [,784] [,785] [,786] [,787]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     96    103     98     55     42    119     75     64     72     64
#> other        4      3      1      2      2      7      5      5      5      3
#>         [,788] [,789] [,790] [,791] [,792] [,793] [,794] [,795] [,796] [,797]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     54     54    115    110     85     81     65     69     59    232
#> other        0      6     10      8      8      8      4      5      2     16
#>         [,798] [,799] [,800] [,801] [,802] [,803] [,804] [,805] [,806] [,807]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    109     77     65    150     70     63    218    216    187    153
#> other        3      4      8      9      9      7     13     14     11      6
#>         [,808] [,809] [,810] [,811] [,812] [,813] [,814] [,815] [,816] [,817]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     92    116    100    322    170     98    125    329    159    124
#> other       11     17      8     32     16     10     13     39     13     12
#>         [,818] [,819] [,820] [,821] [,822] [,823] [,824] [,825] [,826] [,827]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    516    401    300    165     73     22      7     21    165    451
#> other       39     36     25     33      5      0      0      3     21     42
#>         [,828] [,829] [,830]
#> alpha        0      0      0
#> delta        0      0      0
#> omicron    396    232     78
#> other       41     29      3
#> 
#> 
#> attr(,"class")
#> [1] "EpiStrainDynamics.pathogen_structure"
#> [2] "list"                                

# Using a time series object (time argument is optional)
sarscov2_xts <- xts::xts(
  sarscov2[, c("cases", "alpha", "delta", "omicron", "other")],
  order.by = sarscov2$date
)
multiple(
  data = sarscov2_xts,
  case_timeseries = "cases",
  component_pathogen_timeseries = c("alpha", "delta", "omicron", "other")
)
#> $pathogen_structure
#> [1] "multiple"
#> 
#> $pathogen_names
#> [1] "alpha"   "delta"   "omicron" "other"  
#> 
#> $validated_tsbl
#> # A tsibble: 830 x 6 [1D]
#>    index      case_timeseries alpha delta omicron other
#>    <date>               <dbl> <dbl> <dbl>   <dbl> <dbl>
#>  1 2020-09-23            7096     0     0       0    10
#>  2 2020-09-24            7682     0     0       0     7
#>  3 2020-09-25            7318     0     0       0     9
#>  4 2020-09-26            6810     0     0       0    15
#>  5 2020-09-27            7023     0     0       0     5
#>  6 2020-09-28            9983     0     0       0     6
#>  7 2020-09-29           10366     0     0       0    23
#>  8 2020-09-30           12717     0     0       0    54
#>  9 2020-10-01           13357     0     0       0    32
#> 10 2020-10-02           13854     0     0       0    15
#> # ℹ 820 more rows
#> 
#> $data
#> $data$case_timeseries
#>   [1]   7096   7682   7318   6810   7023   9983  10366  12717  13357  13854
#>  [11]  11667  11953  16753  17250  18573  18425  15893  12648  12202  19671
#>  [21]  19116  19920  18606  17915  14882  14311  25872  25613  25714  23475
#>  [31]  21694  16434  15895  26807  24351  23901  23614  22890  16673  15970
#>  [41]  31925  25943  24027  24063  23659  18766  20244  31510  27789  27757
#>  [51]  24826  24388  18223  16233  26952  23488  21076  18041  17100  12533
#>  [61]  11895  19024  16679  16814  14761  14554  11086  10852  18198  16684
#>  [71]  16676  15860  15834  12893  13731  21584  21065  21909  22916  24390
#>  [81]  19588  22266  35197  34378  35427  34437  36419  25589  33066  48192
#>  [91]  46475  42936  32392  14419  41110  48520  46408  83090  72161  53947
#> [101]  32482  61654  56335  77972  66638  58784  53187  48105  40035  37174
#> [111]  58592  50647  46509  43472  41452  31250  29592  45957  40525  35986
#> [121]  32502  30330  22344  17554  30737  27730  26303  24773  22434  17167
#> [131]  15783  22972  20265  19914  18493  16307  12320  11664  16194  14225
#> [141]  13899  13139  12573   9035   8995  14735  12939  11942  11793  10728
#> [151]   8313   8098  11657   9763   8847   8024   6782   4949   4873   7192
#> [161]   6918   6172   5937   5467   4628   4410   6890   6488   6250   5933
#> [171]   5717   4381   4425   6703   5863   5978   5632   5180   4247   5390
#> [181]   6459   5484   6224   5616   4567   3731   5030   4196   3779   3966
#> [191]   3674   2747   2508   2412   2744   3313   3253   3147   2953   2380
#> [201]   2376   2881   2495   2512   2345   2347   1722   2584   2738   2541
#> [211]   2708   2409   2020   1564   2119   2626   2178   2499   2230   1825
#> [221]   1433   1521   2084   2553   2569   2326   1982   1609   2307   2809
#> [231]   2329   2335   2182   1938   1628   1923   2858   2812   2813   2517
#> [241]   2367   2000   2326   3369   3427   3922   3747   3589   3000   3164
#> [251]   3897   5431   6168   6258   5861   4731   5534   7946   7896   8210
#> [261]   8043   7619   6284   7135  10362  10800  11052  11106  10320   8447
#> [271]  10087  16308  17402  18351  18714  18169  16301  18502  28418  28199
#> [281]  28923  28794  26339  24010  25170  34919  36060  38597  34020  32804
#> [291]  28379  30503  44511  47707  54910  62000  55264  38476  36182  47924
#> [301]  39876  35548  31278  27817  22852  22187  29981  29582  30237  28432
#> [311]  24749  20570  20985  29840  30473  32338  31660  28035  22540  22887
#> [321]  32162  31518  33350  31726  28974  25057  25327  36907  37920  38739
#> [331]  36501  32231  28536  28743  39715  37682  38777  37613  33745  27601
#> [341]  26136  34774  45212  43532  42328  38633  31810  31803  44929  38619
#> [351]  35849  33974  29187  23533  24060  34658  31435  30414  29710  29479
#> [361]  26645  31084  40768  38848  36756  35851  32108  28567  32083  41589
#> [371]  36548  34837  32604  29058  26316  32059  43733  39279  39264  38465
#> [381]  35612  32306  36418  50304  48321  47775  46419  43560  37878  43752
#> [391]  57743  52529  51661  45194  40664  35103  35764  47466  42124  43045
#> [401]  41391  40251  33569  34814  45109  38019  35986  33662  30318  27436
#> [411]  30586  44126  42246  42942  40999  37763  32885  35532  50948  46430
#> [421]  45895  44062  39606  35335  37250  50733  48197  46772  43425  39330
#> [431]  33303  39706  56289  55695  54820  50319  45667  38784  41051  59694
#> [441]  56258  58827  56995  52492  48594  53158  87169 102788 112703 106055
#> [451]  95897  88883  89133 133966 150293 161560 160633 137268  70363 116287
#> [461] 195011 212469 272798 236576 188567 118275 181068 229901 275647 222174
#> [471] 172980 120287  93615  95790 132959 115245 103219  96412  86325  77950
#> [481]  98097 131514 118857 111760 100324  91730  81733 102365 127364 113202
#> [491] 108668  96201  84026  73512  87702 105051  93949  88418  76644  63264
#> [501]  52305  60552  76483  69661  64339  52293  44559  37529  41755  54745
#> [511]  52502  51572  44716  33241  34647  37720  45132  39188  36477  30631
#> [521]  27837  25089  31360  44649  44795  46179  43761  41408  38759  49026
#> [531]  68520  70112  73531  70510  67030  62078  75739  99834  93708  91751
#> [541]  82853  75285  67417  81054 109286  99095  94185  82905  72430  61456
#> [551]  68336  92857  80126  73643  54791  47462  37592  42179  53727  49101
#> [561]  44750  38709  32988  27885  30952  37371  33771  31685  26639  21617
#> [571]  19925  20144  25223  25772  21457  18464  15703  13210  14714  17109
#> [581]  14560  13055  11608  10012   8354   9034  11907  13318  11672  10221
#> [591]   8954   7517   9062  10702   9748   8725   7642   6942   6120   7973
#> [601]   9417   8286   7638   6820   5821   5019   5997   7313   6679   6293
#> [611]   5753   5409   4988   5680   7115   7093   7011   6209   6635   7492
#> [621]   9815  11747  11411  11784  11319  10784  10077  12693  15272  15141
#> [631]  14837  14225  13919  13623  16997  19942  20896  20873  19590  18350
#> [641]  16800  20778  25104  25041  24601  24240  23650  21961  27780  33704
#> [651]  31415  29698  26454  24611  21246  25096  29826  26946  23856  21100
#> [661]  18359  15017  17236  18718  16670  16169  14158  12378   9934  11275
#> [671]  13299  11725  10544   9329   8508   7325   8426   9835   9170   8353
#> [681]   7296   6548   5420   6547   8068   7309   6748   6193   5339   4495
#> [691]   5363   6424   5559   5032   4564   4012   3502   4085   5224   4778
#> [701]   4554   3796   3451   3112   3439   4662   5226   4616   4350   3808
#> [711]   3417   4288   5125   4578   4235   3747   3553   3268   4347   5308
#> [721]   5148   4973   4634   4134   3521   4339   6166   7828   7553   6815
#> [731]   6485   5719   7240   8618   8255   8414   7895   7615   7065   9204
#> [741]  11692  10965  10231   9389   8950   7053   8558  10497   9461   8769
#> [751]   8134   7970   6442   7780  10005   8235   7598   6576   6297   4968
#> [761]   5523   6807   5665   5449   4855   4401   3583   4271   5129   4549
#> [771]   4014   3678   3107   2665   3267   4321   3829   3576   3205   2893
#> [781]   2433   2912   3923   3534   3260   3037   2773   2431   2890   3938
#> [791]   3805   3616   3329   2902   2551   3448   4639   4386   3980   3505
#> [801]   3596   2748   3786   5325   5241   5195   4537   4216   3570   4631
#> [811]   6986   7111   6533   6094   6084   4743   5772   9073   8631   7802
#> [821]   6877   5741   4132   3694   4950   6605   8419   7718   6126   4287
#> 
#> $data$component_pathogens
#>         [,1] [,2] [,3] [,4] [,5] [,6] [,7] [,8] [,9] [,10] [,11] [,12] [,13]
#> alpha      0    0    0    0    0    0    0    0    0     0     0     0     0
#> delta      0    0    0    0    0    0    0    0    0     0     0     0     0
#> omicron    0    0    0    0    0    0    0    0    0     0     0     0     0
#> other     10    7    9   15    5    6   23   54   32    15    23     8    35
#>         [,14] [,15] [,16] [,17] [,18] [,19] [,20] [,21] [,22] [,23] [,24] [,25]
#> alpha       0     0     0     0     0     0     0     0     0     0     0     0
#> delta       0     0     0     0     0     0     0     0     0     0     0     0
#> omicron     0     0     0     0     0     0     0     0     0     0     0     0
#> other      39    45    25    18    12    25    47    34    18    11    23    24
#>         [,26] [,27] [,28] [,29] [,30] [,31] [,32] [,33] [,34] [,35] [,36] [,37]
#> alpha       0     0     0     0     0     0     0     0     0     0     0     0
#> delta       0     0     0     0     0     0     0     0     0     0     0     0
#> omicron     0     0     0     0     0     0     0     0     0     0     0     0
#> other      33    47    55    46    21     7     8     9    10     3     3     4
#>         [,38] [,39] [,40] [,41] [,42] [,43] [,44] [,45] [,46] [,47] [,48] [,49]
#> alpha       0     0     3     1     0     0     0     0     1     2     0     0
#> delta       0     0     0     0     0     0     0     0     0     0     0     0
#> omicron     0     0     0     0     0     0     0     0     0     0     0     0
#> other       1     3    22    25     7     6    14    32    14    10    21    25
#>         [,50] [,51] [,52] [,53] [,54] [,55] [,56] [,57] [,58] [,59] [,60] [,61]
#> alpha       1     0     0     0     2     4     1     1     3     3     3     2
#> delta       0     0     0     0     0     0     0     0     0     0     0     0
#> omicron     0     0     0     0     0     0     0     0     0     0     0     0
#> other      18    20    25    26    10    38    14     4    13    11     8    14
#>         [,62] [,63] [,64] [,65] [,66] [,67] [,68] [,69] [,70] [,71] [,72] [,73]
#> alpha       4     6    14     4     4     7     6     3     4     8     0     1
#> delta       0     0     0     0     0     0     0     0     0     0     0     0
#> omicron     0     0     0     0     0     0     0     0     0     0     0     0
#> other      14    14     7     6    10     6    15    11    14     4     1     0
#>         [,74] [,75] [,76] [,77] [,78] [,79] [,80] [,81] [,82] [,83] [,84] [,85]
#> alpha       0     0    18    16    12    12    14     7    10    27    63    57
#> delta       0     0     0     0     0     0     0     0     0     0     0     0
#> omicron     0     0     0     0     0     0     0     0     0     0     0     0
#> other       0     5     5    11    11     7     7     5     5    38    34    52
#>         [,86] [,87] [,88] [,89] [,90] [,91] [,92] [,93] [,94] [,95] [,96] [,97]
#> alpha      64    47    17    30    52    65    69     0     0     1    48    60
#> delta       0     0     0     0     0     0     0     0     0     0     0     0
#> omicron     0     0     0     0     0     0     0     0     0     0     0     0
#> other      46    34    21    16    29    32    29     0     0     0    27    21
#>         [,98] [,99] [,100] [,101] [,102] [,103] [,104] [,105] [,106] [,107]
#> alpha     111    68     15      0     35     50    125     93     67     50
#> delta       0     0      0      0      0      0      0      0      0      0
#> omicron     0     0      0      0      0      0      0      0      0      0
#> other      41    13     14      0     22     18     39     28     21      9
#>         [,108] [,109] [,110] [,111] [,112] [,113] [,114] [,115] [,116] [,117]
#> alpha       55     40     48     81     75     70     38     46     43     45
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other       15     11     17     10     18     18      4      2     12      4
#>         [,118] [,119] [,120] [,121] [,122] [,123] [,124] [,125] [,126] [,127]
#> alpha       67     54     53     39     34     29     17     19     51     53
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        7      4     17      2      6      5      4      6      1      4
#>         [,128] [,129] [,130] [,131] [,132] [,133] [,134] [,135] [,136] [,137]
#> alpha       44     39     22     47     36     26     24     31     18     29
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        4      5      3      5      4      0      1      1      0      1
#>         [,138] [,139] [,140] [,141] [,142] [,143] [,144] [,145] [,146] [,147]
#> alpha        2     33     25     29     23     20     10      8     22     26
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      1      2      1      1      0      2      1      0
#>         [,148] [,149] [,150] [,151] [,152] [,153] [,154] [,155] [,156] [,157]
#> alpha       17      6      5      6      8     13     16     13     11     10
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      1      0      1      0      0      1
#>         [,158] [,159] [,160] [,161] [,162] [,163] [,164] [,165] [,166] [,167]
#> alpha        7     11     10     14     15     11      4      9      6     13
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      1      2      0      3      0      0      1      0      0
#>         [,168] [,169] [,170] [,171] [,172] [,173] [,174] [,175] [,176] [,177]
#> alpha        6     11     10     15     12      8     20      6      6     12
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      1      0      0      0      0      0      2      0      0
#>         [,178] [,179] [,180] [,181] [,182] [,183] [,184] [,185] [,186] [,187]
#> alpha        4      7      8     11      8      8     13      4      8      8
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      1      0      0      0      0      0      0      1      0
#>         [,188] [,189] [,190] [,191] [,192] [,193] [,194] [,195] [,196] [,197]
#> alpha       10     11      9      8      5      3      0      5      7      8
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        1      0      0      0      0      0      0      0      0      0
#>         [,198] [,199] [,200] [,201] [,202] [,203] [,204] [,205] [,206] [,207]
#> alpha        2      5      6     10      8      4      5      6      3      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,208] [,209] [,210] [,211] [,212] [,213] [,214] [,215] [,216] [,217]
#> alpha        1      5      7      3      2      3      3      1      3      4
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      1      0      0      0      0      0      0
#>         [,218] [,219] [,220] [,221] [,222] [,223] [,224] [,225] [,226] [,227]
#> alpha        2      2      5      3      0      5      1      0      1      2
#> delta        1      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,228] [,229] [,230] [,231] [,232] [,233] [,234] [,235] [,236] [,237]
#> alpha        2      0      1      2      3      2      2      0      0      4
#> delta        1      0      0      0      0      0      0      0      0      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,238] [,239] [,240] [,241] [,242] [,243] [,244] [,245] [,246] [,247]
#> alpha        1      2      1      0      0      2      0      2      2      2
#> delta       10      0      0      4      2      1      4      3      3      0
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,248] [,249] [,250] [,251] [,252] [,253] [,254] [,255] [,256] [,257]
#> alpha        1      0      1      0      4      0      2      2      0      0
#> delta        1     10      2      3      7      6      2     10      6      3
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      1      0      0      0      0      0
#>         [,258] [,259] [,260] [,261] [,262] [,263] [,264] [,265] [,266] [,267]
#> alpha        0      0      1      2      1      1      0      2      1      1
#> delta        6     13      8      6      6     10      6     20      9      7
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,268] [,269] [,270] [,271] [,272] [,273] [,274] [,275] [,276] [,277]
#> alpha        0      1      0      0      0      2      0      2      0      0
#> delta        9     18     16      6     22     21     26     26     22     24
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      1      0      1      0      0      0
#>         [,278] [,279] [,280] [,281] [,282] [,283] [,284] [,285] [,286] [,287]
#> alpha        1      0      1      0      1      1      0      1      0      0
#> delta       24     37     29     40     30     39     21     23     55     61
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,288] [,289] [,290] [,291] [,292] [,293] [,294] [,295] [,296] [,297]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta       83     61     63     55     42     73     80     66     94     60
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,298] [,299] [,300] [,301] [,302] [,303] [,304] [,305] [,306] [,307]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta       58     79    111    106    111     94    106     70     55     42
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      1
#>         [,308] [,309] [,310] [,311] [,312] [,313] [,314] [,315] [,316] [,317]
#> alpha        0      0      0      0      0      0      0      0      1      0
#> delta       28     37     54     70     49     49     66     85     70     94
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,318] [,319] [,320] [,321] [,322] [,323] [,324] [,325] [,326] [,327]
#> alpha        0      0      0      0      0      1      0      0      0      0
#> delta       56     40     39     48     64     86     71     64     49     56
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,328] [,329] [,330] [,331] [,332] [,333] [,334] [,335] [,336] [,337]
#> alpha        0      1      0      0      0      0      1      0      0      0
#> delta       70     97     86     49     58     74     65     68     92     80
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,338] [,339] [,340] [,341] [,342] [,343] [,344] [,345] [,346] [,347]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta       73     66     58     53     48    106     82     83     72     73
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,348] [,349] [,350] [,351] [,352] [,353] [,354] [,355] [,356] [,357]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta       58     74     93    107    101     74     66     50     99     86
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,358] [,359] [,360] [,361] [,362] [,363] [,364] [,365] [,366] [,367]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta       75     78     69     70     77     76     88     98    103     96
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,368] [,369] [,370] [,371] [,372] [,373] [,374] [,375] [,376] [,377]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta      103     93    102    119    113    100    104    111    118    127
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,378] [,379] [,380] [,381] [,382] [,383] [,384] [,385] [,386] [,387]
#> alpha        0      0      0      0      0      0      0      0      0      1
#> delta      112    143    122    134    141     87    103    124    161    145
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,388] [,389] [,390] [,391] [,392] [,393] [,394] [,395] [,396] [,397]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta      151    178    156    188    155    179    159    126    141    173
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,398] [,399] [,400] [,401] [,402] [,403] [,404] [,405] [,406] [,407]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta      161    161    184    147    110     94    149    122    150    148
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,408] [,409] [,410] [,411] [,412] [,413] [,414] [,415] [,416] [,417]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta      148    116     94    119    113    124    126    110     95    105
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,418] [,419] [,420] [,421] [,422] [,423] [,424] [,425] [,426] [,427]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta       96    131    166    123     93    116    106    119    119    147
#> omicron      0      0      0      0      0      0      0      0      0      0
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,428] [,429] [,430] [,431] [,432] [,433] [,434] [,435] [,436] [,437]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta      150    128     93    111     97    122    146    125    136    117
#> omicron      0      0      0      0      0      2      0      0      0      1
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,438] [,439] [,440] [,441] [,442] [,443] [,444] [,445] [,446] [,447]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta      121    108     95    137    106    123     85     81     84     95
#> omicron      2      5      6     10     16      7     15     15     26     64
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,448] [,449] [,450] [,451] [,452] [,453] [,454] [,455] [,456] [,457]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta      117    133    111     94     72     70    122    112     87     55
#> omicron     88    124    111    138    150    164    256    331    283    220
#> other        2      0      0      0      0      0      0      1      0      0
#>         [,458] [,459] [,460] [,461] [,462] [,463] [,464] [,465] [,466] [,467]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0     38     37     28     29     15      0     12
#> omicron      0      0      4    335    510    525    520    322      2    410
#> other        0      0      0      1      0      0      0      0      0      0
#>         [,468] [,469] [,470] [,471] [,472] [,473] [,474] [,475] [,476] [,477]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta       15     22     13     10      6      5     13      7      7      5
#> omicron    573    594    579    570    495    410    421    436    500    469
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,478] [,479] [,480] [,481] [,482] [,483] [,484] [,485] [,486] [,487]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        2      3      7      3      4      3      2      1      2      1
#> omicron    334    337    348    341    411    452    329    258    321    327
#> other        0      0      0      0      0      0      0      0      0      0
#>         [,488] [,489] [,490] [,491] [,492] [,493] [,494] [,495] [,496] [,497]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      1      2      0      0      2      0      2      1      0
#> omicron    295    408    450    425    352    303    356    388    475    517
#> other        0      0      0      0      0      0      0      0      1      0
#>         [,498] [,499] [,500] [,501] [,502] [,503] [,504] [,505] [,506] [,507]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        1      0      0      1      0      0      0      2      0      1
#> omicron    501    398    372    319    359    423    400    417    346    281
#> other        0      1      0      0      0      0      0      0      0      0
#>         [,508] [,509] [,510] [,511] [,512] [,513] [,514] [,515] [,516] [,517]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      1      0      0      0      0      0      0      0
#> omicron    316    255    282    329    308    275    201    226    269    265
#> other        0      0      0      2      0      0      0      0      0      0
#>         [,518] [,519] [,520] [,521] [,522] [,523] [,524] [,525] [,526] [,527]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        1      0      0      0      0      0      0      0      0      0
#> omicron    272    274    253    229    237    280    283    289    254    233
#> other        3      1      1      0      0      0      1      0      0      0
#>         [,528] [,529] [,530] [,531] [,532] [,533] [,534] [,535] [,536] [,537]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      2      0      0      0      0      0      0      0
#> omicron    262    300    282    380    385    430    451    435    420    522
#> other        0      0      0      1      0      3      2      2      1      5
#>         [,538] [,539] [,540] [,541] [,542] [,543] [,544] [,545] [,546] [,547]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      1
#> omicron    563    649    614    463    427    394    507    702    752    718
#> other        3      3      7      3      0      4      7      6      3      5
#>         [,548] [,549] [,550] [,551] [,552] [,553] [,554] [,555] [,556] [,557]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    725    590    662    560    831    860    811    673    489    474
#> other        2      5      9      6      9      6     11      3      4      3
#>         [,558] [,559] [,560] [,561] [,562] [,563] [,564] [,565] [,566] [,567]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    479    639    648    558    458    351    294    399    578    588
#> other        4      6      4      6      2      2      4      1      3      4
#>         [,568] [,569] [,570] [,571] [,572] [,573] [,574] [,575] [,576] [,577]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    585    480    367    239      3    355    413    432    370    314
#> other        3      4      0      1      0      4      6      4      1      9
#>         [,578] [,579] [,580] [,581] [,582] [,583] [,584] [,585] [,586] [,587]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    276    204    252    285    196    183    152    133    101    157
#> other        2      2      0      1      0      1      0      0      2      4
#>         [,588] [,589] [,590] [,591] [,592] [,593] [,594] [,595] [,596] [,597]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    166    173    176    109    109    108    145    158    167    127
#> other        1      0      0      2      2      3      1      4      0      0
#>         [,598] [,599] [,600] [,601] [,602] [,603] [,604] [,605] [,606] [,607]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     99    101     88    139    131    154    150    106     78     83
#> other        7      0      0      1      3      1      0      1      1      1
#>         [,608] [,609] [,610] [,611] [,612] [,613] [,614] [,615] [,616] [,617]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    110    118    113     99     85     81     69    115    123    111
#> other        0      0      0      1      0      1      1      0      0      3
#>         [,618] [,619] [,620] [,621] [,622] [,623] [,624] [,625] [,626] [,627]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     84      1    116    103    171    206    190    170    192    119
#> other        0      0      0      0      1      1      2      0      0      0
#>         [,628] [,629] [,630] [,631] [,632] [,633] [,634] [,635] [,636] [,637]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    121    225    187    229    162    156    156    162    253    284
#> other        0      0      2      0      0      0      1      0      1      1
#>         [,638] [,639] [,640] [,641] [,642] [,643] [,644] [,645] [,646] [,647]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    271    245    256    208    228    330    322    325    297    270
#> other        0      0      0      1      0      0      1      0      2      0
#>         [,648] [,649] [,650] [,651] [,652] [,653] [,654] [,655] [,656] [,657]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    229    230    283    299    321    297    241    173    155    291
#> other        0      0      0      0      0      0      1      1      0      0
#>         [,658] [,659] [,660] [,661] [,662] [,663] [,664] [,665] [,666] [,667]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    325    283    312    268    226    151    287    334    373    348
#> other        0      2      0      0      1      1      1      0      1      0
#>         [,668] [,669] [,670] [,671] [,672] [,673] [,674] [,675] [,676] [,677]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    336    180    167    427    340    311    262    181    113     92
#> other        0      0      0      4      1      0      0      2      0      0
#>         [,678] [,679] [,680] [,681] [,682] [,683] [,684] [,685] [,686] [,687]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    201    138    101    118     97     49     27    171    112     69
#> other        0      0      0      0      1      0      0      0      0      0
#>         [,688] [,689] [,690] [,691] [,692] [,693] [,694] [,695] [,696] [,697]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     95     94     58     43    180    103    105     88     92     63
#> other        0      0      0      0      0      0      0      0      0      2
#>         [,698] [,699] [,700] [,701] [,702] [,703] [,704] [,705] [,706] [,707]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     43    162    116    105     64     75     31     23     72    114
#> other        0      0      0      0      0      0      0      0      0      1
#>         [,708] [,709] [,710] [,711] [,712] [,713] [,714] [,715] [,716] [,717]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     42    179     95     59     50    187    125     55     30     38
#> other        1      0      0      0      0      0      0      0      0      0
#>         [,718] [,719] [,720] [,721] [,722] [,723] [,724] [,725] [,726] [,727]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     55     55    182     95    114    119    106     69     22     57
#> other        0      0      0      1      0      3      1      1      0      0
#>         [,728] [,729] [,730] [,731] [,732] [,733] [,734] [,735] [,736] [,737]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    228    179    179    138     83     92    227    167    180    175
#> other        0      0      0      0      1      1      4      2      0      0
#>         [,738] [,739] [,740] [,741] [,742] [,743] [,744] [,745] [,746] [,747]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    102     61     95    274    237    262    301    246    126     90
#> other        0      1      2      2      1      0      2      1      0      2
#>         [,748] [,749] [,750] [,751] [,752] [,753] [,754] [,755] [,756] [,757]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    369    257    188    118    259    102    101    398    242    162
#> other        2      1      1      2      3      1      4     12      9      7
#>         [,758] [,759] [,760] [,761] [,762] [,763] [,764] [,765] [,766] [,767]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     65    247    105     56    207     78    254    170    177     70
#> other        2      8      2      0      2      1      5      2      5      2
#>         [,768] [,769] [,770] [,771] [,772] [,773] [,774] [,775] [,776] [,777]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     68    177    124    121    119    126     51     65    135    110
#> other        1      6      5      4      5      2      2      2      6      2
#>         [,778] [,779] [,780] [,781] [,782] [,783] [,784] [,785] [,786] [,787]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     96    103     98     55     42    119     75     64     72     64
#> other        4      3      1      2      2      7      5      5      5      3
#>         [,788] [,789] [,790] [,791] [,792] [,793] [,794] [,795] [,796] [,797]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     54     54    115    110     85     81     65     69     59    232
#> other        0      6     10      8      8      8      4      5      2     16
#>         [,798] [,799] [,800] [,801] [,802] [,803] [,804] [,805] [,806] [,807]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    109     77     65    150     70     63    218    216    187    153
#> other        3      4      8      9      9      7     13     14     11      6
#>         [,808] [,809] [,810] [,811] [,812] [,813] [,814] [,815] [,816] [,817]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron     92    116    100    322    170     98    125    329    159    124
#> other       11     17      8     32     16     10     13     39     13     12
#>         [,818] [,819] [,820] [,821] [,822] [,823] [,824] [,825] [,826] [,827]
#> alpha        0      0      0      0      0      0      0      0      0      0
#> delta        0      0      0      0      0      0      0      0      0      0
#> omicron    516    401    300    165     73     22      7     21    165    451
#> other       39     36     25     33      5      0      0      3     21     42
#>         [,828] [,829] [,830]
#> alpha        0      0      0
#> delta        0      0      0
#> omicron    396    232     78
#> other       41     29      3
#> 
#> 
#> attr(,"class")
#> [1] "EpiStrainDynamics.pathogen_structure"
#> [2] "list"