Skip to contents

Main genome retrieval function for an organism of interest. By specifying the scientific name of an organism of interest the corresponding fasta-file storing the genome of the organism of interest can be downloaded and stored locally. Genome files can be retrieved from several databases. In addition, the genome summary statistics for the retrieved species is stored locally to provide users with insights regarding the genome assembly quality (see summary_genome for details). This is useful when comparing genomes with large difference in genome assembly qualities.


  db = "refseq",
  reference = FALSE,
  skip_bacteria = TRUE,
  release = NULL,
  gunzip = FALSE,
  path = file.path("_ncbi_downloads", "genomes"),
  assembly_type = "toplevel",
  mute_citation = FALSE,
  analyse_genome = FALSE



a character string specifying the database from which the genome shall be retrieved:

  • db = "refseq"

  • db = "genbank"

  • db = "ensembl"


Organism selector id, there are three options to characterize an organism:

  • by scientific name: e.g. organism = "Homo sapiens"

  • by database specific accession identifier: e.g. organism = "GCF_000001405.37" (= NCBI RefSeq identifier for Homo sapiens)

  • by taxonomic identifier from NCBI Taxonomy: e.g. organism = "9606" (= taxid of Homo sapiens)


a logical value indicating whether or not a genome shall be downloaded if it isn't marked in the database as either a reference genome or a representative genome.


Due to its enormous dataset size (> 700MB as of July 2023), the bacterial summary file will not be loaded by default anymore. If users wish to gain insights for the bacterial kingdom they needs to actively specify skip_bacteria = FALSE. When skip_bacteria = FALSE is set then the bacterial summary file will be downloaded.


a numeric, the database release version of ENSEMBL (db = "ensembl"). Default is release = NULL meaning that the most recent database version is used. release = 75 would for human would give the stable GRCh37 release in ensembl. Value must be > 46, since ensembl did not structure their data if the standard format before that.


a logical, indicating whether or not files should be unzipped.


character, default location is paste0("set_", toupper(type))


character, default c("primary_assembly", "toplevel"). Used for ensembl only, specifies the genome assembly type. Searches for both primary and toplevel, and if both are found, uses the first by order (so primary is prioritized by default). The Primary assembly should usually be used if it exists. The "primary assembly" contains all the top-level sequence regions, excluding alternative haplotypes and patches. If the primary assembly file is not present for a species (only defined for standard model organisms), that indicates that there were no haplotype/patch regions, and in such cases, the 'toplevel file is used. For more details see: ensembl tutorial


logical, default FALSE, indicating whether citation message should be muted.


logical, default FALSE. If TRUE, get general genome statistics like gc content etc. For more details, see ?summary_genome


File path to downloaded genome.


Internally this function loads the the overview.txt file from NCBI:



and creates a directory relative to file type, if you get fasta genomes it will be _ncbi_downloads/genomes'. In case the corresponding fasta file already exists within the '_ncbi_downloads/genomes' folder and is accessible within the workspace, no download process will be performed. For other file types the same rule applies.

See also

Other getBio: getBio(), getCDS(), getCollection(), getGFF(), getProteome(), getRNA()

Other genome: getGenomeSet(), read_genome()


Hajk-Georg Drost