Drug properties that have been experimentally proven
Value
a tibble with the following variables:
- kind
Name of the property.
- value
Drug properties that have been experimentally proven.
- source
Reference to the source of this experimental data.
- drugbank_id
drugbank id
The following experimental properties are provided:
- Water Solubility
The experimentally determined aqueous solubility of the molecule.
- Molecular Formula
Protein formula of Biotech drugs
- Molecular Weight
Protein weight of Biotech drugs.
- Melting Point
The experimentally determined temperature at which the drug molecule changes from solid to liquid at atmospheric temperature.
- Boiling Point
The experimentally determined temperature at which the drug molecule changes from liquid to gas at atmospheric temperature.
- Hydrophobicity
The ability of a molecule to repel water rather than absorb or dissolve water.
- Isoelectric Point
The pH value at which the net electric charge of a molecule is zero.
- caco2 Permeability
A continuous line of heterogenous human epithelial colorectal adenocarcinoma cells, CAC02 cells are employed as a model of human intestinal absorption of various drugs and compounds. CAC02 cell permeability is ultimately an assay to measure drug absorption.
- pKa
The experimentally determined pka value of the molecule
- logP
The experimentally determined partition coefficient (LogP) based on the ratio of solubility of the molecule in 1-octanol compared to water.
- logS
The intrinsic solubility of a given compound is the concentration in equilibrium with its solid phase that dissolves into solution, given as the natural logarithm (LogS) of the concentration.
- Radioactivity
The property to spontaneously emit particles (alpha, beta, neutron) or radiation (gamma, K capture), or both at the same time, from the decay of certain nuclides.